News

Jul,21,2015: Version 1.0 released.

Cite this article as:

Zhang, X., Li, M., Lin, H. et al. Hum Genet (2017). doi:10.1007/s00439-017-1783-x



** Note: Input file MUST be in VCF format. Sample input: here Try it!

Select features to be displayed on result page:
Length of involved exon and neighboring introns
Proximity to donor/acceptor sites
conservation of +/- 7bp around variant
Junction sites strength
change of junction score
Splicing factors matching score
Magnitude of changing of RNA binding proteins'(RBPs) binding affinity(Caution: 201 features)
post-prob of changing of RBPs' binding affinity(Caution: 201 features)
cluster score - changing of ESE/ESS motifs
PTM - Post-translational modification sites
Pfam - percenrage of Pfam domains coverage
Disorder score
SS - Secondary structure of affected protein region
ASA - Accessible Surface Area
EF score - probability of single strandness around variant
RNA 2nd structure change